We are in tireless pursuit of breakthroughs that improve patients' lives. We drive innovation daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it still holds true today. Research confirms what we instinctively know: that purpose-driven companies deliver better results, are more creative, recruit and maintain the best talent, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and embodies the value we aim to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We live our purpose by finding the best science in the world, working with others in the healthcare system to increase access to our medicines, utilizing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.