We are in relentless pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a more healthy place. It was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what we instinctively know: that purpose-driven companies achieve more, are more innovative, attract and retain the best people, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and represents the value we work to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We live our purpose by finding the best science in the world, partnering with others in the healthcare system to increase access to our medicines, using digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.