We're in constant pursuit of breakthroughs that improve patients' lives. We drive innovation daily to make the world a better place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more creative, attract and retain the best people, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and embodies the value we strive to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, utilizing digital technologies to advance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.