We are in constant pursuit of breakthroughs that transform patients' lives. We create innovations every day to make the world a more healthy place. This was Charles Pfizer's original vision, and it remains true today. Research confirms what we instinctively know: that purpose-driven companies achieve more, are more inventive, attract and retain the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and shows our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and represents the value we strive to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We live our purpose by finding the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.