We are in relentless pursuit of breakthroughs that transform patients' lives. We create innovations every day to make the world a better place. This was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what we instinctively know: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best professionals, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and reflects our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has meaning and reflects the value we work to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We embody our purpose by seeking the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every choice we make, and every move we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.