We are in constant pursuit of breakthroughs that change patients' lives. We innovate daily to make the world a healthier place. It was Charles Pfizer's founding vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more creative, attract and retain the best talent, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and demonstrates our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and reflects the value we aim to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We live our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can prosper.