We are in constant pursuit of breakthroughs that transform patients' lives. We create innovations daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it holds true today. Studies show what intuition tells us: that purpose-driven companies achieve more, are more innovative, draw and keep the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we work to bring to patients and society. Our purpose ensures that patients remain at the heart of all we do. We fulfill our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.