We are in tireless pursuit of breakthroughs that transform patients' lives. We drive innovation daily to make the world a healthier place. It was Charles Pfizer's initial vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more creative, draw and keep the best people, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and reflects our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we work to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.