We are in constant pursuit of breakthroughs that change patients' lives. We innovate daily to make the world a healthier place. It was Charles Pfizer's founding vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, draw and keep the best people, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that improve patients' lives—fuels everything we do and shows our passion for expanding our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and reflects the value we work to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We live our purpose by sourcing the best science in the world, partnering with others in the healthcare system to improve access to our medicines, utilizing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.