We are in constant pursuit of breakthroughs that transform patients' lives. We create innovations daily to make the world a healthier place. This was Charles Pfizer's founding vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more innovative, draw and keep the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and represents the value we strive to bring to patients and society. Our purpose ensures that patients remain at the core of all we do. We fulfill our purpose by finding the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.