We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a healthier place. This was Charles Pfizer's original vision, and it still holds true today. Studies show what intuition tells us: that purpose-driven companies deliver better results, are more inventive, draw and keep the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and reflects our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and reflects the value we aim to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We live our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.