We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a more healthy place. This was Charles Pfizer's initial vision, and it holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more inventive, draw and keep the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and demonstrates our passion for expanding our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and reflects the value we strive to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We embody our purpose by finding the best science in the world, working with others in the healthcare system to improve access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.