We are in relentless pursuit of breakthroughs that change patients' lives. We innovate each day to make the world a better place. It was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more inventive, recruit and maintain the best talent, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has meaning and reflects the value we strive to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We embody our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.