We are in constant pursuit of breakthroughs that change patients' lives. We create innovations every day to make the world a healthier place. This was Charles Pfizer's founding vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more innovative, draw and keep the best people, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and embodies the value we strive to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, working with others in the healthcare system to increase access to our medicines, using digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.