We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, recruit and maintain the best people, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and demonstrates our passion for growing our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and represents the value we work to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We fulfill our purpose by seeking the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, using digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.