We are in constant pursuit of breakthroughs that change patients' lives. We innovate each day to make the world a more healthy place. This was Charles Pfizer's initial vision, and it still holds true today. Studies show what we instinctively know: that purpose-driven companies achieve more, are more inventive, recruit and maintain the best people, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and represents the value we aim to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We live our purpose by finding the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.