We are in constant pursuit of breakthroughs that improve patients' lives. We innovate every day to make the world a healthier place. This was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, draw and keep the best professionals, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and represents the value we strive to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We embody our purpose by finding the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and driving the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.