We are in constant pursuit of breakthroughs that improve patients' lives. We drive innovation daily to make the world a better place. It was Charles Pfizer's initial vision, and it holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more inventive, attract and retain the best people, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—fuels everything we do and reflects our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and represents the value we work to bring to patients and society. Our purpose makes certain that patients continue to be at the core of all we do. We live our purpose by sourcing the best science in the world, partnering with others in the healthcare system to improve access to our medicines, using digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.