We are in tireless pursuit of breakthroughs that transform patients' lives. We create innovations each day to make the world a healthier place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies achieve more, are more creative, draw and keep the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and shows our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has meaning and represents the value we work to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, working with others in the healthcare system to improve access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and driving the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.