We are in constant pursuit of breakthroughs that change patients' lives. We create innovations each day to make the world a better place. It was Charles Pfizer's initial vision, and it still holds true today. Studies show what we instinctively know: that purpose-driven companies achieve more, are more creative, draw and keep the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—drives everything we do and reflects our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and represents the value we strive to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We live our purpose by finding the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.