We are in tireless pursuit of breakthroughs that transform patients' lives. We innovate daily to make the world a more healthy place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more innovative, attract and retain the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and demonstrates our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we work to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We fulfill our purpose by seeking the best science in the world, partnering with others in the healthcare system to improve access to our medicines, using digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.